Amyloid- Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle
نویسندگان
چکیده
منابع مشابه
Understanding the sleep-wake cycle: sleep, insomnia, and the orexin system.
This Academic Proceedings Supplement to The Journal of Clinical Psychiatry presents the highlights of the planning roundtable teleconference “Understanding the Sleep-Wake Cycle: Sleep, Insomnia, and the Orexin System,” which was held on May 24, 2013. This report was prepared and independently developed by the CME Institute of Physicians Postgraduate Press, Inc., and was supported by an educatio...
متن کاملOrexin system: roles in sleep/wake regulation
*KURAに登録されているコンテンツの利用については,著作権法に規定されている私的使用や引用などの範囲内で行ってください。 *著作権法に規定されている私的使用や引用などの範囲を超える利用を行う場合には,著作権者の許諾を得てください。ただし,著作権者 から著作権等管理事業者(学術著作権協会,日本著作出版権管理システムなど)に権利委託されているコンテンツの利用手続については ,各著作権等管理事業者に確認してください。 Title The orexin system: Roles in sleep/wake regulation Author(s) Sakurai, Takeshi; Mieda, Michihiro; Tsujino, Natsuko Citation Bulletin of the Japanese Society of Scientific Fisheries = A...
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BACKGROUND Scale-invariant neuronal avalanches have been observed in cell cultures and slices as well as anesthetized and awake brains, suggesting that the brain operates near criticality, i.e. within a narrow margin between avalanche propagation and extinction. In theory, criticality provides many desirable features for the behaving brain, optimizing computational capabilities, information tra...
متن کامل[Sleep-wake cycle mechanisms].
Neurochemically distinct systems interact regulating sleep and wakefulness. Wakefulness is promoted by aminergic, acetylcholinergic brainstem and hypothalamic systems. Each of these arousal systems supports wakefulness and coordinated activity is required for alertness and EEG activation. Neurons in the pons and preoptic area control rapid eye movement and non-rapid eye movement sleep. Mutual i...
متن کاملDelayed orexin signaling consolidates wake and sleep : physiology and modeling
Orexin-producing neurons are clearly essential for the regulation of wakefulness and sleep as loss of these cells produces narcolepsy. However, little is understood about how these neurons dynamically interact with other wakeand sleep-regulatory nuclei to control behavioral states. Using survival analysis of wake bouts in wild type and orexin knockout mice, we found that orexins are necessary f...
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ژورنال
عنوان ژورنال: Science
سال: 2009
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.1180962